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Trump warns of serious retaliation after deadly ISIS ambush kills US troops in Syria

The killing of American personnel during a routine mission in Syria has triggered a sharp response from the United States leadership, with warnings that those responsible will face forceful consequences.

The incident has also raised fresh questions about security conditions in parts of Syria that remain unstable despite changes in the country’s political leadership.

On Saturday, December 13, 2025, an attack in central Syria claimed the lives of two US service members and a civilian interpreter who was also from the United States.

Three more American troops were injured in the incident, alongside at least two Syrian soldiers. Officials said this was the first attack to result in US casualties since Syrian President Bashar al-Assad was removed from power a year ago, a moment that had raised hopes of improved stability in some areas.

US President Donald Trump responded strongly after being briefed on the attack. In a post on Truth Social, he confirmed that the wounded American soldiers were recovering and warned that the assault would not go unanswered.

“This was an ISIS attack against the U.S. and Syria, in a very dangerous part of Syria, that is not fully controlled by them,” Trump wrote.

“The President of Syria, Ahmed al-Sharaa, is extremely angry and disturbed by this attack. There will be very serious retaliation.”

Trump’s comments reflected the position of the US government, which described the incident as an ambush carried out by a lone ISIL gunman.

According to official statements, the attacker was later engaged and killed. US Secretary of Defence Pete Hegseth issued a separate warning, making it clear that the United States would pursue anyone responsible for harming its citizens abroad.

“Let it be known, if you target Americans anywhere in the world, you will spend the rest of your brief, anxious life knowing the United States will hunt you, find you, and ruthlessly kill you,” Hegseth wrote on X.

The Pentagon said the attack occurred near Palmyra as US soldiers were conducting what it described as a key leader engagement.

Pentagon spokesperson Sean Parnell explained that the mission was part of ongoing counter-ISIS and counter-terrorism operations in the region.

He noted that the area where the attack occurred remains dangerous and not fully under government control.

Further details were provided by Tom Barrack, the US ambassador to Turkiye, who described the incident as a “cowardly terrorist ambush targeting a joint U.S.–Syrian government patrol”.

He confirmed that Syrian troops were among those wounded and wished them a speedy recovery, underlining the joint nature of the operation.

Despite these statements, many aspects of the attack remain unclear. US Central Command said it would withhold the identities of the fallen soldiers and their units until 24 hours after their families had been notified.

The US Department of Defence also confirmed that the incident remains under active investigation.

The attack has once again highlighted the persistent threat posed by ISIL, even after years of military pressure and political shifts in Syria.